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James Gagnon

Assistant Professor

Graduate Program Membership:

Office/Building: CSC 132C
Phone: 801-581-5716
Gagnon Lab:

Research Statement

Vertebrate lineage and cell fate choice, cell signaling, genome engineering

Research Interests

General Interests

Selected Publications

  • Raj B, Wagner DW, McKenna A, Pandey S, Klein AM, Shendure J, Gagnon JA*, Schier AF*. Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain by scGESTALT. Nature Biotechnology 2018.
  • Gagnon JA, Obbad K, Schier AF. The primary role of zebrafish nanog is in extraembryonic tissue. Development 2018.
  • McKenna A*, Findlay G*, Gagnon JA*, Horwitz M, Schier AF, Shendure J. Whole organism lineage tracing by combinatorial and cumulative genome editing. Science 2016 353:aaf7907
  • Gagnon JA, Valen E, Thyme SB, Huang P, Akhmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. PLoS One 2014 9:e98186
  • Montague TG*, Cruz JM*, Gagnon JA, Church GM, Valen E. CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing. Nucleic Acids Res. 2014 42:W401-7