Jody Rosenblatt

Adjunct Assistant Professor of Biology and Assistant Professor of Oncology Science

Office/Building: HCI 5344
Phone: 801-587-4073
Email: jody.rosenblatt@hci.utah.edu

Research Statement

For normal tissue homeostasis, cells within a tissue maintain constant numbers by matching cell death with cell division. The epithelium is one of the largest tissues in the body and is continuously undergoing cell renewal. We study how cells within the epithelium turnover since misregulation of homeostasis is at the heart of epithelial tumor (carcinoma) formation.

Selected Publications

1. Slattum G*, McGee K*, and Rosenblatt J. P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium. J Cell Biol. 2009 Sep 7;186(5):693-702.
2. Rosenblatt J. Mitosis: moesin and the importance of being round. Curr Biol. 2008 Apr 8;18(7): 292-3.
3. Rosenblatt J (2005) Spindle assembly: asters part their separate ways. Nature Cell Biology, 7(3): 219-22
4. Rosenblatt J, Cramer LP, Baum B, and McGee KM (2004) Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly. Cell 117(3): 361-372
5. Rosenblatt J, Raff MC, and Cramer LP (2001) An epithelial cell destined for apoptosis signals its neighbours to extrude it by an actin-and myosin-dependent mechanism. Current Biology 11:1847-1857