I study how bacterial pathogens evolve and spread in plant host populations, and how hosts in turn evolve resistance. My current work aims to elucidate the genetic and population-level mechanisms that prevent the emergence of epidemics. My research touches upon several disciplines within the Biological Sciences including population genetics, microbial and plant genomics and classical microbiology.
- Host-parasite evolution
- Microbial genetics
- Microbial ecology
- Plant Evolutionary Genetics
- 1. Karasov TL, Almario J, Friedemann C, Ding W, Giolai M, Heavens D, Kersten S, Lundberg DS, Neumann M, Regalado J, et al.: Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations over Evolutionary Timescales. Cell Host Microbe 2018, 24:168–179.e4.
- 2. Karasov TL, Chae E, Herman JJ, Bergelson J: Mechanisms to Mitigate the Trade-Off between Growth and Defense. Plant Cell 2017, 29:666–680.
- 3. Karasov TL, Kniskern JM, Gao L, DeYoung BJ, Ding J, Dubiella U, Lastra RO, Nallu S, Roux F, Innes RW, et al.: The long-term maintenance of a resistance polymorphism through diffuse interactions. Nature 2014, 512:436–440.
- 4. Regalado J, Lundberg DS, Deusch O, Kersten S, Karasov T, Poersch K, Shirsekar G, Weigel D: Combining whole-genome shotgun sequencing and rRNA gene amplicon analyses to improve detection of microbe--microbe interaction networks in plant leaves. ISME J 2020, 1-15